To address how the ZP domain functions in the assembly of the egg matrix, Jovine et al. 2 developed a model system to study incorporation of modified zona pellucida proteins into the egg's ...

The human zona pellucida is composed of four glycoproteins (ZP1, ZP2, ZP3, and ZP4) and has an important role in reproduction. Here we describe a form of infertility with an autosomal recessive mod ...