A longstanding obstacle to the market for bovine embryos is about to be removed. Researchers have described a hitherto unknown mechanism of lipid accumulation in oocytes that limits the success of ...

They depleted KIFC1 protein in mouse and bovine oocytes using a new method co-developed in Schuh's lab called Trim-Away. This technique rapidly degrades almost any target protein in any type of cell.

The oocyte is the female gamete, and it holds all the ‘ingredients’ necessary to support embryo development. The idea for the project came from the fact that bovine embryo in-vitro production ...

The scientists next investigated whether manipulation of the protein level affects spindle stability. They depleted KIFC1 protein in mouse and bovine oocytes using a new method co-developed in Schuh‘s ...

In a recent study, researchers in Europe described a cleanup pathway operating in young oocytes in mice (Cell 2024, DOI: 10.1016/j.cell.2024.01.031).The process involves collections of lysosomes ...

A recent study involving murine stem cells showed a recapitulation of the entire female germline life cycle, which resulted in fertilizable mouse oocytes in culture. Among approximately 200 resulta ...